draxxin dosage for cattle per pound pdf
Draxxin Dosage for Cattle⁚ A Comprehensive Guide
This guide provides a comprehensive overview of Draxxin dosage for cattle, addressing key aspects like administration, contraindications, and safety information. It also delves into Draxxin’s use for specific conditions like foot rot and the combined solution Draxxin KP. The information will be helpful for livestock owners and veterinarians seeking to understand optimal Draxxin usage for cattle.
Understanding Draxxin
Draxxin, also known by its generic name tulathromycin, is a highly effective antibiotic specifically designed for the treatment of bovine respiratory disease (BRD) in cattle. It belongs to the macrolide class of antibiotics and works by inhibiting the growth of bacteria responsible for BRD, such as Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.
Draxxin is available in two formulations⁚ Draxxin 25 Injectable Solution and Draxxin 100 Injectable Solution. The concentration of tulathromycin differs between the two, with Draxxin 25 containing 25 mg of tulathromycin per mL and Draxxin 100 containing 100 mg of tulathromycin per mL.
The effectiveness of Draxxin stems from its unique mechanism of action. It effectively targets the ribosomes of bacteria, which are crucial for protein synthesis. By interfering with this process, Draxxin effectively inhibits bacterial growth and prevents further infection. This targeted approach makes Draxxin a valuable tool for controlling BRD in cattle, which can significantly impact herd health and productivity.
Dosage and Administration
The recommended dosage of Draxxin for cattle is 2.5 mg of tulathromycin per kilogram of body weight, which translates to 1.1 mL per 100 pounds of body weight. This dosage is typically administered as a single subcutaneous injection in the neck region of the animal. The injection site should be carefully selected to minimize the risk of injection site reactions.
For cattle weighing over 300 kg (660 lbs), it’s recommended to divide the dose into multiple injection sites to avoid exceeding the maximum volume of 10 mL per injection site. This ensures proper drug distribution and minimizes the risk of tissue damage.
It’s important to use a sterile needle and syringe to administer Draxxin, ensuring aseptic technique to prevent contamination. The injection site should be cleaned with an antiseptic solution before and after the injection. After administering the injection, monitor the animal for any adverse reactions and consult with a veterinarian if any concerns arise.
The recommended dosage and administration guidelines for Draxxin are crucial for achieving the desired therapeutic effect and minimizing potential risks. Following these guidelines ensures optimal treatment outcomes and promotes the well-being of the cattle.
Draxxin Dosage Chart
The following chart provides a clear and concise guide to Draxxin dosage for cattle based on their weight. It’s crucial to use this chart as a reference to determine the correct dosage for each animal.
| Animal Weight (Pounds) | Dose Volume (mL) |
|---|---|
| 100 | 1.1 |
| 200 | 2.3 |
| 300 | 3.4 |
| 400 | 4.5 |
| 500 | 5.7 |
| 600 | 6.8 |
| 700 | 8.0 |
| 800 | 9.1 |
| 900 | 10.2 |
| 1000 | 11.4 |
This chart serves as a handy tool for livestock owners and veterinarians to ensure accurate Draxxin administration. It allows for precise dosage calculation based on the weight of the animal, promoting optimal treatment outcomes and minimizing potential risks associated with incorrect dosage.
Contraindications
Understanding contraindications for Draxxin is crucial for ensuring safe and effective treatment. It’s essential to avoid administering Draxxin in situations where it could potentially cause harm or adverse reactions. Here are key contraindications to consider⁚
- Hypersensitivity⁚ Draxxin should not be used in animals with a known history of hypersensitivity to tulathromycin, the active ingredient. If an animal has previously exhibited allergic reactions to Draxxin, it’s imperative to avoid future administration.
- Combined Solution⁚ Draxxin KP, a combined solution of tulathromycin and ketoprofen, is contraindicated in animals with hypersensitivity to either of these ingredients. Carefully review the animal’s history and avoid using Draxxin KP if a sensitivity exists to either tulathromycin or ketoprofen.
- Dairy Cattle⁚ Draxxin is not approved for use in lactating dairy cattle; This restriction is in place to prevent potential residues of tulathromycin from contaminating milk products intended for human consumption.
- Pregnant Animals⁚ While Draxxin has not been shown to cause significant harm to pregnant animals, it’s best to avoid using it during pregnancy unless absolutely necessary. Consult with a veterinarian to weigh the risks and benefits in individual cases.
By carefully adhering to these contraindications, livestock owners and veterinarians can minimize the risks associated with Draxxin use and ensure the well-being of their animals.
Draxxin for Other Livestock
While Draxxin is primarily known for its use in cattle, its effectiveness extends to other livestock species, making it a versatile treatment option for various animal health needs. However, it’s crucial to understand the specific dosage and administration guidelines for each species, as they can vary.
- Swine⁚ Draxxin is approved for treating and controlling swine respiratory disease (SRD) in swine. The recommended dosage for swine is 2.5 mg/kg body weight, administered intramuscularly as a single injection. Consult the product label for detailed information on dosage and administration for swine.
- Sheep⁚ Draxxin is also effective in treating respiratory disease in sheep. The dosage for sheep is 2.5 mg/kg body weight, administered subcutaneously as a single injection. As with other livestock, it’s essential to follow the specific instructions on the product label for sheep.
It’s vital to consult with a veterinarian before administering Draxxin to any livestock species. They can provide tailored advice based on the specific animal’s health condition, weight, and potential contraindications. By seeking professional guidance, you can ensure the safe and effective use of Draxxin for your livestock.
Draxxin for Foot Rot
Foot rot, also known as infectious pododermatitis, is a painful and debilitating condition in cattle that can significantly impact herd health and productivity. Draxxin has proven effective in treating the early stages of foot rot associated with virulent Dichelobacter nodosus, which requires systemic treatment.
The recommended dosage for treating foot rot in cattle is a single subcutaneous injection of 2.5 mg tulathromycin/kg body weight, equivalent to 1 ml/40 kg body weight. For cattle exceeding 300 kg body weight, the dose should be divided to ensure no more than 7.5 ml are injected at a single site.
Studies have demonstrated the efficacy of Draxxin in treating foot rot. In one study, cattle diagnosed with foot rot were treated with a single subcutaneous dose of Draxxin (2.5 mg/kg BW) or a saline solution. After seven days, the Draxxin-treated cattle showed a significant reduction in lesion size, swelling, and lameness compared to the control group. This highlights the potential of Draxxin to effectively manage foot rot and improve animal welfare.
While Draxxin is a valuable tool for treating foot rot, it’s essential to consult with a veterinarian for a proper diagnosis and to determine the most suitable treatment plan for your cattle. Early detection and prompt treatment are crucial for minimizing the impact of foot rot on herd health and productivity.
Safety Information
While Draxxin is generally well-tolerated by cattle, there are important safety considerations to keep in mind. It’s crucial to follow the recommended dosage and administration guidelines to minimize the risk of adverse effects.
One key safety concern is the pre-slaughter withdrawal time. Draxxin has a pre-slaughter withdrawal time of 18 days in cattle, meaning that cattle treated with Draxxin should not be slaughtered for meat consumption for at least 18 days after the injection. This is to ensure that residue levels of the drug in the meat are below safe limits.
Another important safety consideration is the injection site. Draxxin should be injected subcutaneously in the neck, and it’s crucial to avoid injecting more than 10 mL per injection site. This helps prevent tissue damage and discomfort. If multiple injections are required, they should be given at different locations to minimize localized reactions.
While Draxxin is generally safe for use in cattle, it’s important to be aware of potential side effects. Some cattle may experience transient reactions at the injection site, such as swelling, redness, or pain. In rare cases, more serious side effects, such as anaphylaxis, may occur. If you observe any concerning reactions, it’s essential to contact a veterinarian immediately.
As with any medication, proper storage is crucial for maintaining the efficacy and safety of Draxxin. It should be stored in a cool, dry place, protected from direct sunlight. The product should also be protected from freezing, as this can damage the medication.
Draxxin KP⁚ A Combined Solution
For cattle producers seeking a comprehensive solution for bovine respiratory disease (BRD) and associated fever, Draxxin KP (tulathromycin and ketoprofen injection) Injectable Solution offers a convenient one-shot combination. This product combines the antimicrobial action of tulathromycin, as found in Draxxin, with the anti-inflammatory and analgesic effects of ketoprofen.
This combined approach provides a powerful tool for managing BRD by addressing both the underlying infection and the associated fever. The synergistic action of tulathromycin and ketoprofen can lead to faster recovery and improved animal welfare. Draxxin KP offers a practical advantage by simplifying treatment and potentially reducing the need for multiple injections.
The combination of tulathromycin and ketoprofen in Draxxin KP provides a targeted approach to BRD management. Tulathromycin’s antimicrobial activity effectively targets the bacterial pathogens commonly associated with BRD, while ketoprofen’s anti-inflammatory and analgesic properties help manage the inflammation and pain often associated with the condition.
When considering Draxxin KP, it is important to note that it has a pre-slaughter withdrawal time of 18 days in cattle. This means that cattle treated with Draxxin KP should not be slaughtered for meat consumption for at least 18 days after the injection. Additionally, Draxxin KP is not intended for use in female dairy cattle that are 1 year of age or older.
Draxxin Dosage for Calves
Calves, being more susceptible to respiratory infections, often require specific considerations when it comes to Draxxin administration. The dosage for calves is typically the same as for adult cattle, which is 2.5 mg tulathromycin per kg body weight, or equivalently, 1 ml per 40 kg body weight. However, the administration method and volume per injection site may differ.
For calves weighing less than 300 kg, a single subcutaneous injection of Draxxin is typically sufficient. However, for calves weighing over 300 kg, the dose should be divided to ensure no more than 7.5 ml are injected at any single site. This approach minimizes the risk of injection site reactions and ensures optimal drug absorption.
It’s crucial to carefully follow the manufacturer’s instructions regarding the dosage and administration of Draxxin for calves. Consult with a veterinarian to determine the appropriate dosage and treatment duration based on the calf’s individual condition and weight. Always prioritize careful administration and adhere to the recommended withdrawal times for meat and milk.
While Draxxin is effective in treating respiratory infections in calves, it’s essential to consider preventive measures like vaccination and proper hygiene to minimize the risk of these infections; A comprehensive approach involving vaccination, biosecurity, and appropriate antibiotic use can contribute to optimal calf health and performance.